منابع مشابه
Studies on the active site of pig kidney aldehyde reductase.
observed in enzyme-methotrexate complexes. The orientation that appears to be required for catalysis can be readily achieved by rotations of the pteridine of 180° around the C-6-C-9 bond and 30° about the C-9-N-10 bond. In this orientation, C-4 of the NADPH nicotinamide ring closely approaches C-6 of the substrate, and N-5 of the substrate is adjacent to aspartic acid-30 of the enzyme. It has b...
متن کاملA Report on Finding a New Peptide Aldehyde from Cyanobacterium Nostoc sp. Bahar M by LC-MS and Marfey’s Analysis
Background: Cyanobacteria have a worldwide distribution in the terrestrial habitats, occurring predominantly on the surface of the soils, stones, rocks, and trees, practically in moist, neutral or alkaline aeries. The unique natural and bioactive compounds from cyanobacteria with various biological activities and an extensive range of chemical classes have a significant capabil...
متن کاملA silver-aldehyde reaction for studies of chromosome ultrastructure
A method is presented for the visualization of structures containing deoxyribonucleic acid at the electron microscope level. This is achieved by the substitution of an ammoniacal silver reagent for leucobasic fuchsin in a Feulgen-like procedure. Tissue aldehydes reduce this reagent to metallic silver, which is deposited at the reactive sites in the form of fine particles. The particles range in...
متن کاملStudies on expression of aldehyde dehydrogenase in normal and cancerous tissues of thyroids.
Recently published articles have reported the controversial data regarding expression of aldehyde dehydrogenase isozyme 1A1 (ALDH1A1), a potential candidate marker for normal and cancer stem cells (CSCs), in thyroid tissues. These data prompted us to re-evaluate expression of ALDH1A1 in normal and cancerous thyroid tissues by 2 different means. The first method was immunohistochemistry with 2 d...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Japanese Journal of Pharmacology
سال: 1973
ISSN: 0021-5198
DOI: 10.1016/s0021-5198(19)61728-2